|
Cellular Processes
|
Cell communication
|
Focal adhesion
|
98
|
2D
|
Down
|
2D
|
Down
|
|
Gap junction
|
39
| | |
2D
|
Down
|
|
Cell growth and death
|
Cell cycle – yeast
|
54
|
Up
|
Up
|
Up
|
Up
|
|
Transport and catabolism
|
Phagosome
|
76
|
Down
|
Down/Mixed
|
Down
|
Down/Mixed
|
|
Endocytosis
|
105
|
Down/2D
|
Down
|
Down/2D
|
Down
|
|
Peroxisome
|
54
|
Up
|
Up
|
Up
|
Up
|
|
Environmental Information Processing
|
Membrane transport
|
ABC transporters
|
27
| | |
Up
|
Mixed
|
|
Signal transduction
|
MAPK signaling pathway
|
110
|
2D
|
Down
|
2D
|
Down
|
|
NF-kappa B signaling pathway
|
64
|
2D
|
Down
| | |
|
Jak-STAT signaling pathway
|
56
|
2D
|
Down
| | |
|
Calcium signaling pathway
|
72
|
2D
|
Down
|
2D
|
Down
|
|
PI3K-Akt signaling pathway
|
149
|
2D
|
Down/Mixed
|
Down/2D
|
Down
|
|
VEGF signaling pathway
|
28
| | |
2D
|
Down
|
|
Signaling molecules and interaction
|
Cell adhesion molecules (CAMs)
|
64
|
2D
|
Down/Mixed
|
2D
|
Down
|
|
Neuroactive ligand-receptor interaction
|
112
|
Down/2D
|
Down
| | |
|
Cytokine-cytokine receptor interaction
|
94
|
Down/2D
|
Down
|
2D
|
Down
|
|
Genetic Information Processing
|
Replication and repair
|
DNA replication
|
33
| | |
Up
|
Up
|
|
Transcription
|
RNA polymerase
|
27
|
Up
|
Up
|
Up
|
Up
|
|
Spliceosome
|
109
| | |
Up
|
Up
|
|
Translation
|
Ribosome biogenesis in eukaryotes
|
64
|
Up
|
Up
|
Up
|
Up/Mixed
|
|
RNA transport
|
111
|
Up
|
Up
|
Up
|
Up/Mixed
|
|
Ribosome
|
118
|
Up
|
Up/Mixed
|
Up
|
Up/Mixed
|
|
Metabolism
|
Amino acid metabolism
|
Arginine and proline metabolism
|
36
|
Up
|
Up
| | |
|
Carbohydrate metabolism
|
Amino sugar & nucleotide sugar metabolism
|
35
|
Up
|
Up/Mixed
|
Up
|
Up/Mixed
|
|
Galactose metabolism
|
16
|
Up
|
Up/Mixed
|
Up
|
Up/Mixed
|
|
Fructose and mannose metabolism
|
19
|
Up
|
Up/Mixed
|
Up
|
Up/Mixed
|
|
Glycolysis / Gluconeogenesis
|
30
|
Up
|
Up/Mixed
| | |
|
Lipid metabolism
|
Sphingolipid metabolism
|
21
|
Up
|
Up
|
Up
|
Up
|
|
Biosynthesis of unsaturated fatty acids
|
15
|
Up
|
Up/Mixed
|
Up
|
Up/Mixed
|
|
Glycerolipid metabolism
|
25
|
Up
|
Up/Mixed
| | |
|
Primary bile acid biosynthesis
|
12
|
Up
|
Up/Mixed
|
Up
|
Up/Mixed
|
|
Nucleotide metabolism
|
Pyrimidine metabolism
|
73
|
Up
|
Up/Mixed
|
Up
|
Up
|
|
Xenobiotics biodegradation and metabolism
|
Drug metabolism - cytochrome P450
|
11
|
Down
|
Down/Mixed
|
Down/2D
|
Down/Mixed
|
|
Organismal Systems
|
Circulatory system
|
Vascular smooth muscle contraction
|
55
|
2D
|
Down
|
Down/2D
|
Down
|
|
Development
|
Osteoclast differentiation
|
69
|
2D
|
Down
|
2D
|
Down
|
|
Axon guidance
|
52
|
Down/2D
|
Down
| | |
|
Digestive system
|
Protein digestion and absorption
|
40
|
2D
|
Mixed
| | |
|
Vitamin digestion and absorption
|
17
|
2D
|
Up/Mixed
| | |
|
Mineral absorption
|
25
|
Up
|
Up/Mixed
| | |
|
Fat digestion and absorption
|
19
|
Up
|
Up/Mixed
|
Up
|
Up/Mixed
|
|
Bile secretion
|
39
|
Up/2D
|
Up/Mixed
|
Up/2D
|
Up
|
|
Salivary secretion
|
32
| | |
Down/2D
|
Down
|
|
Endocrine system
|
Ovarian steroidogenesis
|
22
|
2D
|
Down
|
2D
|
Down
|
|
Thyroid hormone synthesis
|
33
|
2D
|
Up/Mixed
| | |
|
PPAR signaling pathway
|
42
|
Up
|
Up
| | |
|
Insulin secretion
|
37
| | |
2D
|
Down
|
|
Environmental adaptation
|
Circadian entrainment
|
45
|
2D
|
Down
|
Down/2D
|
Down
|
|
Immune system
|
T cell receptor signaling pathway
|
61
|
2D
|
Down
| | |
|
Fc epsilon RI signaling pathway
|
29
|
2D
|
Down
|
2D
|
Down/Mixed
|
|
B cell receptor signaling pathway
|
39
|
2D
|
Down
|
Down/2D
|
Down
|
|
Complement and coagulation cascades
|
56
|
Down
|
Down/Mixed
|
Down
|
Down/Mixed
|
|
Hematopoietic cell lineage
|
38
|
Down/2D
|
Down/Mixed
|
Down
|
Down
|
|
Chemokine signaling pathway
|
88
|
Down/2D
|
Down/Mixed
|
Down/2D
|
Down/Mixed
|
|
Natural killer cell mediated cytotoxicity
|
40
|
Down/2D
|
Down/Mixed
|
Down/2D
|
Down
|
|
Nervous system
|
Glutamatergic synapse
|
50
|
2D
|
Down
|
Down/2D
|
Down
|
|
Synaptic vesicle cycle
|
35
|
Down
|
Down
| | |
|
Serotonergic synapse
|
49
|
Down
|
Down
|
Down
|
Down
|
|
Retrograde endocannabinoid signaling
|
46
| | |
2D
|
Down
|
|
Sensory system
|
Phototransduction
|
14
|
Down
|
Down
| | |