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|
Genotype
| |
All
| |
Male
| |
Female
|
|---|
|
LRRTM4
|
CPQ
|
n
|
Sus
|
Res
|
P-val.
|
n
|
Sus
|
Res
|
P-val.
|
n
|
Sus
|
Res
|
P-val.
|
|---|
|
AG
|
TA
|
23
|
56.5
|
43.5
|
0.375
|
11
|
45.5
|
54.5
|
3.067
|
11
|
63.6
|
36.4
|
1.081
|
|
AG
|
YM
|
26
|
50.0
|
50.0
|
6.107
|
12
|
44.4
|
55.6
|
5.380
|
12
|
57.1
|
42.9
|
8.443
|
|
AG
|
CC
|
72
|
36.4
|
63.6
|
6.910
|
36
|
50.0
|
50.0
|
7.575
|
31
|
0
|
100.0
|
3.449
|
|
RR
|
TA
|
33
|
33.3
|
66.7
|
1.488
|
18
|
25.0
|
75.0
|
2.340
|
7
|
41.7
|
58.3
|
3.371
|
|
RR
|
YM
|
31
|
42.9
|
57.1
|
4.935
|
15
|
46.7
|
53.3
|
2.026
|
12
|
27.3
|
72.7
|
3.259
|
|
RR
|
CC
|
131
|
25.8
|
74.2
|
0.080
|
61
|
14.8
|
85.2
|
0.033
|
53
|
36.5
|
63.5
|
4.818
|
|
GA
|
TA
|
15
|
38.8
|
61.2
|
4.198
|
8
|
30.6
|
69.4
|
2.488
|
2
|
48.4
|
51.6
|
2.139
|
|
GA
|
YM
|
14
|
25.8
|
74.2
|
0.620
|
8
|
14.8
|
85.2
|
0.582
|
5
|
36.5
|
63.5
|
3.403
|
|
GA
|
CC
|
54
|
40.0
|
60.0
|
6.187
|
19
|
44.4
|
55.6
|
2.382
|
26
|
3.8
|
69.2
|
2.661
|
- SNP genotype data for LRRTM4 and CPQ genes were combined and evaluated relative to distribution with respect to ascites phenotype. The CC non-reference homozygote was previously associated with resistance (35). Statistical analyses of association was based on adjusted P-values comparing observed counts vs predicted counts based on HWE. Genotype for LRRTM4 is as described in Table 2. Genotype for CPQ is for SNPs corresponding to bases 127,010,709 and 127,010,716 on chromosome 2 [34]
